What is the usage of anastrozole?
This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Anastrozole belongs to nonsteroidal aromatase inhibitors class medications. It works by decreasing the amount of estrogen the body makes.
How long should you be on anastrozole?
In primary breast cancer, if you take anastrozole as your only hormone therapy, then you will usually take it for five years. Some people may recommend to take anastrozole for five years after completing five years of tamoxifen (ten years of hormone therapy in total).
What does anastrozole do to your body?
Anastrozole tablets work by cutting down the amount of the hormone called estrogen that your body makes. It does this by blocking a natural substance (an enzyme) in your body called ‘aromatase’.
Is anastrozole better than tamoxifen?
Earlier ATAC results found that Arimidex was more effective than tamoxifen in reducing the risk of recurrence of early-stage. Hormone-receptor-positive breast cancer in postmenopausal women. Other studies comparing tamoxifen to the other two aromatase inhibitors (Aromasin and Femara) have shown similar results.
What is the half life of anastrozole?
Elimination of anastrozole is primarily via hepatic metabolism (approximately 85%) and to a lesser extent, renal excretion (approximately 11%), and anastrozole has a mean terminal elimination half-life of approximately 50 hours in postmenopausal women.
Does anastrozole cause hair loss?
Some women who take the breast cancer hormone treatments tamoxifen, anastrozole, letrozole and exemestane may also experience hair thinning because of the oestrogen-lowering effect of these treatments. However, these treatments are unlikely to cause complete hair loss.